Once you have the basic machines and solid power generation in Mekanism, it’s probably time to start making more advanced machines and tools. To do this you will have to do one of the most boring things in Minecraft, mining. You need to have at least half a stack of iron and osmium as well as about 10 diamonds, along with other items. Then the next thing you should make is Refined Obsidian Ingots. You use these to make the Atomic Disissembler and Robit, which you can use to make the Digital Miner. Then you should make a number of Atomic Alloys, which are made by putting Enriched Alloys in a Metallurgic Infuser with first diamonds and then Refined Obsidian in the slot on the left. These alloys are needed in most high tier items.